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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEK8
All Species:
24.55
Human Site:
T667
Identified Species:
41.54
UniProt:
Q86SG6
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86SG6
NP_835464.1
692
74806
T667
L
D
E
T
H
P
Y
T
V
T
S
V
S
C
C
Chimpanzee
Pan troglodytes
XP_511801
843
90571
T818
L
D
E
T
H
P
Y
T
V
T
S
V
S
C
C
Rhesus Macaque
Macaca mulatta
XP_001106986
781
84378
T756
L
D
E
T
H
P
Y
T
V
T
S
V
S
C
C
Dog
Lupus familis
XP_548291
727
78319
T702
L
D
E
I
H
P
Y
T
V
T
S
V
S
C
C
Cat
Felis silvestris
Mouse
Mus musculus
Q91ZR4
698
75246
M673
L
D
E
T
H
P
Y
M
V
T
S
V
S
C
C
Rat
Rattus norvegicus
NP_001099274
698
75236
T673
L
D
E
T
H
P
Y
T
V
T
S
V
S
C
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512532
832
89432
V651
L
D
E
P
H
P
Y
V
V
T
S
V
S
C
C
Chicken
Gallus gallus
XP_415822
728
79098
V673
L
E
E
T
H
P
Y
V
V
T
S
V
A
C
C
Frog
Xenopus laevis
Q7ZZC8
944
104521
H691
P
I
F
G
S
L
H
H
V
T
D
L
S
C
R
Zebra Danio
Brachydanio rerio
Q90XC2
697
76523
T672
L
D
E
S
H
A
F
T
V
T
S
V
A
C
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_490968
998
111830
E936
D
L
K
S
K
I
K
E
Q
D
T
T
F
E
G
Sea Urchin
Strong. purpuratus
XP_001201534
446
48490
R422
L
P
P
Q
H
R
A
R
S
V
C
C
G
V
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9CAU7
606
68016
K582
L
R
P
F
G
P
G
K
V
S
P
R
E
T
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48479
858
94329
S792
Q
Q
Q
S
N
T
N
S
I
S
S
S
N
S
A
Conservation
Percent
Protein Identity:
100
75.4
87
88.8
N.A.
93.5
93.4
N.A.
68.7
76.9
24.7
73.8
N.A.
N.A.
N.A.
23.2
38.2
Protein Similarity:
100
76.9
87.8
91
N.A.
96.4
95.4
N.A.
74
85.1
39.5
85.2
N.A.
N.A.
N.A.
37.8
50.8
P-Site Identity:
100
100
100
93.3
N.A.
93.3
100
N.A.
86.6
80
26.6
73.3
N.A.
N.A.
N.A.
0
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
100
N.A.
86.6
93.3
40
93.3
N.A.
N.A.
N.A.
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.2
N.A.
21.7
Protein Similarity:
N.A.
N.A.
N.A.
44
N.A.
37.1
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
8
0
0
0
0
0
15
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
8
0
72
65
% C
% Asp:
8
58
0
0
0
0
0
0
0
8
8
0
0
0
8
% D
% Glu:
0
8
65
0
0
0
0
8
0
0
0
0
8
8
0
% E
% Phe:
0
0
8
8
0
0
8
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
0
8
8
0
8
0
0
0
0
0
8
0
8
% G
% His:
0
0
0
0
72
0
8
8
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
8
0
8
0
0
8
0
0
0
0
0
0
% I
% Lys:
0
0
8
0
8
0
8
8
0
0
0
0
0
0
0
% K
% Leu:
79
8
0
0
0
8
0
0
0
0
0
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
8
0
0
0
0
0
8
0
0
% N
% Pro:
8
8
15
8
0
65
0
0
0
0
8
0
0
0
0
% P
% Gln:
8
8
8
8
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
8
0
0
0
8
0
8
0
0
0
8
0
0
8
% R
% Ser:
0
0
0
22
8
0
0
8
8
15
72
8
58
8
0
% S
% Thr:
0
0
0
43
0
8
0
43
0
72
8
8
0
8
0
% T
% Val:
0
0
0
0
0
0
0
15
79
8
0
65
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
58
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _